It's up to 2 processors, so you can get started with just one.
If you're thinking about buying a second one later on, think twice now, because buying a second equal processor is probably quite difficult (and expensive) later on. But on the other hand you will save quite some money if one processor is enough for you.
For board details see:
http://www.intel.com/products/server/motherboards/s5520hc/s5520hc-overview.htm