Further to my previous comment. Any backup software you choose should support block-level de-duplication. This will significantly reduce the amount of disk space required for backups. Some companies offer de-duplication to Tape too. Block level de-duplication can save up to 90% on disk space.
http://www.commvault.com/solutions-deduplication.htmlAs JNL2000 sad I would all so recommend backing up to disk first and then moving the data to tape.
CommVault has a very good backup solutions which supports de-duplication to disk and to tape.