Question : Best practice for external hard drive gaming

I recently installed a game on my external hard drive.  Whenever I want to play a game, I turn on the computer let it start up and then turn on the external hard drive.  The drive is connected via USB.

Is this the best way, or should I keep the drive on all the time?  Should I defrag it?  If so, how frequently and should I use any specific software or should I just use the Windows defragger?  Is there anything else I should know to keep this hard drive in good shape?  

Thanks.

Answer : Best practice for external hard drive gaming

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