Hi
I have virtualize many File Servers
After you virtualize a Server, then you can treated as a normal Physical Server regarding the security.
The performance, just need to create the Server, create a Virtual Disk to hold the files(here you can use a normal disk or a LUN connected directly to the server a RAW disk). The write/read performance will always depend your Storage to hold your Data Files
If you need more information just ask please
Jail