Hi
Did you make any changes in the network recently ?
Are 443 80 25 ports - open in firewall and forwarding to exchange server ?
Please check these links for RPC endpoint errors.
http://msexchangeteam.com/archive/2008/06/20/449053.aspxPorts 6001 6002 6004 -> should be open between Exchange Server and DC.
Please check here in registry if ValidPorts key is set for these ports
HKEY_LOCAL_MACHINE\SOFTWAR
E\Microsof
t\Rpc\RpcP
roxy
Tests:
a) Can you browse to this location.
https://mail.fqdn.com/rpc/rpcproxy.dllb) From your exchange server
Start>run>cmd
type
rpccfg.exe /hd
rpcdump /s FQDN.MAILSERVER
More details here
http://support.microsoft.com/kb/908472http://forums.msexchange.org/m_1800521362/mpage_1/key_/tm.htm#1800521470