Question : Upgrade ESX 4.0U1 to 4.1

I've got an ESX host running 4.0 U1.  On it is a VM with a trial version of Virtual Center 4.1 installed.  Can I upgrade the host to 4.1 using update manager even though the VC server is in a VM on the same host?

BTW, I'm installing a fresh copy of 4.1 on a separate host tomorrow.  Worst case I could migrate the VC VM to this host to perform the upgrade of the other server.

Answer : Upgrade ESX 4.0U1 to 4.1

They haven't updated the Upgrade Guide in that link yet...it's on the documentation link for 4.1. Here it is:
http://www.vmware.com/pdf/vsphere4/r41/vsp_41_upgrade_guide.pdf

I haven't ran 4.1 upgrade yet, but what I did for 4 was the similar suggestion you made above...I migrated VMs off my host, disconnected my datastore storage (SAN-based, so all I did was disconnect my fibre), performed fresh install on my host, reconnected my shared storage, then migrated VMs back (then I upgraded VMware Tools then Hardware on my VMs). It's more cautious this way...and I tend to side with the way of caution :)

~coolsport00