So, he is copying files from the server to a local drive, working on them, and then moving them back to the server? No problems? That does seem to point to something network-related. That only makes sense though if AutoCAD LT is somehow more sensitive to network performance/issues than the other apps you say work fine even when LT is locked up.
As a test, you could run a new patch cable from a different router or patch panel port. You could also try a different NIC. Has his current cable to the box suffered any foot or chair traffic?
Lee